N-Functionalised polyfluoropyridazin-3(2H)-one derivatives

  • Pattison G
  • Sandford G
  • Yufit D
 et al. 
  • 3


    Mendeley users who have this article in their library.
  • 8


    Citations of this article.


Pyridazin-3(2H)-one systems have very useful biological properties and have found many applications within the pharmaceutical and agrochemical industries but, in general, synthesis of polysubstituted analogues can be very difficult to achieve. An approach to the syntheses of polyfunctional pyridazinone systems involving sequential nucleophilic substitution reactions of N-aryl and N-THP protected 4,5,6-trifluoropyridazin-3(2H)-ones as the core scaffolds is described. © 2009 Elsevier Ltd. All rights reserved.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Graham PattisonUniversity of Warwick

  • Graham Sandford

  • Dmitry S. Yufit

  • Judith A.K. Howard

  • John A. Christopher

  • David D. Miller

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free