An opsonised electrode. The direct electrochemical detection of superoxide generated by human neutrophils

  • Green M
  • Hill H
  • Tew D
 et al. 
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Abstract

A pyrolytic graphite electrode was surface modified with human IgG and used as a stimulus to elicit a respiratory burst from human neutrophils. The oxidation current observed was shown to be due to re-oxidation of superoxide produced by the neutrophils. Both superoxide dismutase and N-ethylmaleimide were effective inhibitors of the oxidation current. © 1984.

Author-supplied keywords

  • Electrochemical detection
  • Human neutrophil
  • N-Ethylmaleimide
  • Superoxide

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Authors

  • Monika J. Green

  • H. Allen O. Hill

  • David G. Tew

  • Nicholas J. Walton

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