Overexpression of the BCL2 gene in a Sertoli-Leydig cell tumor of the ovary: A pathologic and cytogenetic study

  • Truss L
  • Dobin S
  • Rao A
 et al. 
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Abstract

A case of virilizing ovarian Sertoli-Leydig cell tumor overexpressing the BCL2 gene and including a novel clonal chromosomal rearrangement of chromosome 18, der(5)t(5;18)(p13;q12),+6,+12, der(18)r(5;18)(p15.3p13;p11.3q12) is described. Further studies of these rare tumors are necessary to ascertain the significance of the findings. © 2004 Elsevier Inc. All rights reserved.

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Authors

  • Lisa Truss

  • Sheila M. Dobin

  • Arundati Rao

  • Ludvik R. Donner

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