A periodic ultrastructure in intermediate filaments

  • Henderson D
  • Geisler N
  • Weber K
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Abstract

Intermediate sized filaments reconstituted in vitro from purified desmin, epidermal keratin and the Mr68,000 protein of neurofilaments were examined after high resolution metal shadowing. The filaments demonstrate a marked longitudinal periodicity of about 21 nm. This is the first procedure that allows detection of a periodic substructure in these filaments using the electron microscope. © 1982.

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Authors

  • David Henderson

  • Norbert Geisler

  • Klaus Weber

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