Phenylcyanoguanidines as inhibitors of glucose-induced insulin secretion from beta cells

  • Tagmose T
  • Mogensen J
  • Agerholm P
 et al. 
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Abstract

3,5-Disubstituted-phenylcyanoguanidines have been identified as activators of SUR1/Kir6.2 potassium channels and as potent inhibitors of insulin release from pancreatic beta cells in vitro. © 2001 Elsevier Science Ltd.

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Authors

  • Tina M. Tagmose

  • John P. Mogensen

  • Pia C. Agerholm

  • Per O G Arkhammar

  • Anne Worsaae

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