The polymorphic phase behavior of dielaidoylphosphatidylethanolamine (DEPE) has been investigated using spectrophotometry and31P nuclear magnetic resonance (NMR). It has been demonstrated that the bilayer to inverted hexagonal phase transition can be observed by spectrophotometry. The effects of the methanol, ethanol, and propanol on both the gel to liquid crystal transition and the bilayer to inverted hexagonal transition were investigated by spectrophotometry. It was shown that these alcohols shift the gel to liquid-crystalline phase transition to lower temperature, whereas the bilayer to inverted hexagonal phase transition is shifted to higher temperatures by these alcohols. The structural transition between the bilayer and inverted hexagonal phase of pure DEPE was also investigated by31P-NMR. © 1989.
Veiro, J. A., Khalifah, R. G., & Rowe, E. S. (1989). The polymorphic phase behavior of dielaidoylphosphatidylethanolamine. Effect of n-alkanols. BBA - Biomembranes, 979(2), 251–256. https://doi.org/10.1016/0005-2736(89)90441-0