Potassium ions play a role in the glycine-induced inhibition of rat substantia nigra zona compacta neurones

14Citations
Citations of this article
7Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Glycine directly inhibits the firing, it hyperpolarizes and/or depolarizes the dopaminergic neurones and increases the membrane conductance. In voltage clamp experiments (near resting potential) either outward and/or inward currents were produced. These actions were present in tetrodotoxin and in 0-calcium-cobalt-treated slices and were antagonized by strychnine. The hyperpolarization depended on the extracellular concentration of potassium and was prevented by cesium diffusion into the cell. Thus potassium ions participate in the glycine mediated inhibition of the firing of substantia nigra zona compacta cells. © 1988.

Cite

CITATION STYLE

APA

Biagio Mercuri, N., Calabresi, P., & Bernardi, G. (1988). Potassium ions play a role in the glycine-induced inhibition of rat substantia nigra zona compacta neurones. Brain Research, 462(1), 199–203. https://doi.org/10.1016/0006-8993(88)90607-5

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free