Practical route for N,O-heteroatom interchange in 3,5-disubstituted-4-nitroisoxazoles

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Abstract

Reaction of 3-methyl-4-nitro-5-alkylisoxazoles with hydroxylamine provides a practical means to interchange the N,O-heteroatoms on the isoxazole core thereby expanding the range of compounds obtainable from 3-methyl-4-nitro-5-styrylisoxazoles. © 2007 Elsevier Ltd. All rights reserved.

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Adamo, M. F. A., Donati, D., Sarti-Fantoni, P., & Buccioni, A. (2008). Practical route for N,O-heteroatom interchange in 3,5-disubstituted-4-nitroisoxazoles. Tetrahedron Letters, 49(6), 941–944. https://doi.org/10.1016/j.tetlet.2007.12.019

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