Three new pyranoquinoline alkaloids, simulenoline, peroxysimulenoline and benzosimuline, together with 22 known compounds, were isolated from the stem bark of Formosan Zanthoxylum simulans. Structures including zanthodioline, a known alkaloid without published data, were elucidated by spectral evidences. Among the isolates, 14 compounds showed strong anti- platelet aggregation activity in vitro.
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