Regulation of tyrosine hydroxylase and choline acetyltransferase activities by cell density in the PC12 rat pheochromocytoma clonal cell line

50Citations
Citations of this article
2Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The specific activities of tyrosine hydroxylase and choline acetyltransferase are more than 10-fold higher in PC12 pheochromocytoma cells at high cell density (8 × 105cells/cm2) as compared to those at low density (104cells/cm2). Co-cultivation of cells at high and low densities or cultivation of cells at the same density but either singly or in large clumps of 50-200 cells indicates that it is a specific intercellular contact rather than release into the culture medium of a conditioning factor which is responsible for the increased activities observed. © 1979.

Cite

CITATION STYLE

APA

Lucas, C. A., Edgar, D., & Thoenen, H. (1979). Regulation of tyrosine hydroxylase and choline acetyltransferase activities by cell density in the PC12 rat pheochromocytoma clonal cell line. Experimental Cell Research, 121(1), 79–86. https://doi.org/10.1016/0014-4827(79)90446-4

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free