Reticulo-facial enkephalinergic pathway in the rat: An experimental immunohistochemical study

  • Senba E
  • Tohyama M
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Enkephalins have been detected in the cranial motor nuclei and may play a role in the motor system. The afferent source of leucine-enkephalin-like immunoreactive fibers in the facial nucleus was investigated using experimental immunohistochemistry. These leucine-enkephalin-containing fibers were markedly reduced on the operated side after the destruction of the ventrolateral part of the caudal medullary reticular formation, where a number of leucine-enkephalin-positive cell bodies were observed. This fact strongly suggests that these leucine-enkephalin-positive cells project ipsilaterally to the facial nucleus and so could have some effects on facial motoneurons. © 1983.

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  • E. Senba

  • M. Tohyama

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