Rotometer for recording rotation in chemically or electrically stimulated rats

  • Schwarz R
  • Stein J
  • Bernard P
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Abstract

An improved rotometer is described which accurately records circling behavior (rotation) in rats with an imbalance of the nigrostriatal pathways. Results of circling induced by apomorphine in rats with unilateral 6-hydroxydopamine lesions of the substantia nigra and circling elicited by electrical stimulation of the nigrostriatal pathway are presented. © 1978.

Author-supplied keywords

  • 6-Hydroxydopamine
  • Apomorphine
  • Circling behavior
  • Electrical stimulation
  • Nigrostriatal pathway
  • Rotometer

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Authors

  • R. D. Schwarz

  • J. W. Stein

  • P. Bernard

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