Sarafotoxin receptors mediate phosphoinositide hydrolysis in various rat brain regions

  • Kloog Y
  • Ambar I
  • Kochva E
 et al. 
  • 5


    Mendeley users who have this article in their library.
  • 33


    Citations of this article.


Sarafotoxin-b, a potent snake vasoconstrictor peptide homologous to the mammalian endothelial vasoconstrictor endothelin, induces phosphoinositide (PI) hydrolysis in various brain regions of the rat. Sarafotoxin-b induced PI hydrolysis is largely independent of extracellular Ca2+and is detected in all brain regions where toxin-binding sites are found. These results point to the existence of a hitherto undetected neuroreceptor associated with the PI cycle. © 1989.

Author-supplied keywords

  • (Rat brain)
  • Endothelin
  • Phosphoinositide
  • Receptor
  • Sarafotoxin
  • Snake venom

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Y. Kloog

  • I. Ambar

  • E. Kochva

  • Z. Wollberg

  • A. Bdolah

  • M. Sokolovsky

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free