In search for internal complexation in cyclodextrin-fullerene conjugates

  • Filippone S
  • Rassat A
  • 4


    Mendeley users who have this article in their library.
  • 16


    Citations of this article.


Three new 2:1 cyclodextrin-fullerene (CD-F) conjugates have been prepared, two β-CD-F (1b and 1c) and one γ-CD-F (1d), of general formula C60[C(COO-X-COOR)2] (1b : X = CH2, 1c, X = CH2CH2OCH2; R = NH-PMBCD (1b,c) or NH-PMGCD (1d), i.e. a β- (1b,c) or γ- (1d) CD, fully methylated except at one primary position, where OH is substituted by NH); they have been compared with the previously described compound 1a (X = (CH2)11, R = NH-PMBCD). The solubility in water at neutral pH of the new molecules is the highest reported to date, greater than 250 mg ml-1. UV and NMR spectra show that aggregates are present in these water solutions. The UV spectra suggest that, at the same concentration of conjugate in water, the percentage of aggregates decreases in the order 1a > 1b ∼ 1d > 1c. No evidence of internal complexation of the fullerene moiety by the CD was detected. © 2003 Académie des sciences. Published by Éditions scientifiques et médicales Elsevier SAS. All rights reserved.

Author-supplied keywords

  • Aggregates
  • Complexation
  • Methanofullerene
  • Permethylcyclodextrin
  • Solubility in water

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Salvatore Filippone

  • André Rassat

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free