A 26 kDa peptide has been cleaved from the C-terminus of the S1 heavy chain with formic acid. Cleavage occurs in the '50 kDa' domain probably at the Asp-600-Pro-601 bond. This fragment has been renatured in the presence of the A2 light chain and the 26 kDa(A2) complex shown to interact with actin in an ATP-sensitive manner. © 1989.
Griffiths, A. J., & Trayer, I. P. (1989). Selective cleavage of skeletal myosin subfragment-1 to form a 26 kDa peptide which shows ATP-sensitive actin binding. FEBS Letters, 242(2), 275–278. https://doi.org/10.1016/0014-5793(89)80484-3