Sequential N-acylamide methylenation-enamide ring-closing metathesis: A synthetic entry to 1,4-dihydroquinolines

  • Bennasar M
  • Roca T
  • Monerris M
 et al. 
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A new synthetic entry to the 1,4-dihydroquinoline nucleus is reported. The procedure involves the dimethyltitanocene methylenation of N-(alkoxycarbonyl) amides derived from 2-allylanilines, followed by ring-closing metathesis of the resulting enamides. © 2005 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • 1,4-Dihydroquinolines
  • Dimethyltitanocene
  • Enamides
  • Olefination
  • Ring-closing metathesis

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  • M. L. Bennasar

  • Tomàs Roca

  • Manuel Monerris

  • Davinia García-Díaz

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