Sequential N-acylamide methylenation-enamide ring-closing metathesis: A synthetic entry to 1,4-dihydroquinolines

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Abstract

A new synthetic entry to the 1,4-dihydroquinoline nucleus is reported. The procedure involves the dimethyltitanocene methylenation of N-(alkoxycarbonyl) amides derived from 2-allylanilines, followed by ring-closing metathesis of the resulting enamides. © 2005 Elsevier Ltd. All rights reserved.

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Bennasar, M. L., Roca, T., Monerris, M., & García-Díaz, D. (2005). Sequential N-acylamide methylenation-enamide ring-closing metathesis: A synthetic entry to 1,4-dihydroquinolines. Tetrahedron Letters, 46(23), 4035–4038. https://doi.org/10.1016/j.tetlet.2005.04.028

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