By improvement of the classical SOCl2-pyridine method for the preparation of acid chlorides, amides and optically pure peptides were synthesized rapidly in a simple manner from DCHA dicyclohexylammonium) salts of carboxylic acids. This modified SOCl2-pyridine method was applied to a rapid synthesis of TRH. © 1985.
Matsuda, F., Itoh, S., Hattori, N., Yanagiya, M., & Matsumoto, T. (1985). A simple method for synthesis of amides and peptides through acyl chlorides. A rapid synthesis of thyrotropin releasing hormone. Tetrahedron, 41(18), 3625–3631. https://doi.org/10.1016/S0040-4020(01)91381-X