The disulphide bonds of Naja nivea toxin α react stoichiometrically with dithioerythritol in the absence of denaturing agents. At an equimolar concentration of dithioerythritol to toxin, one disulphide is cleaved selectively. Alkylation leads to a derivative which retains toxicity and antigenicity. © 1974.
Botes, D. P. (1974). Snake venom toxins. The reactivity of the disulphide bonds of Naja nivea toxin α. BBA - Protein Structure, 359(2), 242–247. https://doi.org/10.1016/0005-2795(74)90220-7