A solitary cutaneous tumor with distinct areas of verruca and seborrheic keratosis-like lesion

2Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

A single, exophytic, cutaneous tumor on the thigh of a 52-year-old man was examined by light microscopy, in situ hybridization and immunohistochemistry. It demonstrated distinct areas of verruca and of seborrheic keratosis-like morphology simultaneously. Focally, architectural abnormalities were noted in some deeper parts of the tumor, but there was no morphological evidence of malignancy. The patient has remained disease-free for two a half years after surgery. Biotinylated full genomic DNA probes of HPV confirmed the presence of types 6/11 exclusive in the verrucous portion of the neoplasm. In the verrucous component p53 protein was overexpressed and, additionally, increased Ki-67 immunopositive signals were detected, being localized below the HPV-DNA-expressing spinous cells.

Cite

CITATION STYLE

APA

Lazaris, A. C., Paraskevakou, H., & Davaris, P. S. (1999). A solitary cutaneous tumor with distinct areas of verruca and seborrheic keratosis-like lesion. Pathology and Oncology Research, 5(4), 320–323. https://doi.org/10.1053/paor.1999.0195

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free