Stimulation of non-specific host resistance against Sendai virus and Escherichia coli infections by chitin derivatives in mice

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Abstract

The efficacy of chitin derivatives on non-specific host resistance to Sendai virus and Escherichia coli infections was studied in mice. Seventy percent deacetylated chitin (DAC-70) and N-trimethylated DAC-70 [DAC-70(Me)3] showed protective activity against Sendai virus infection; however, carboxymethyl-chitin (CM-chitin) did not. DAC-70 also showed protective activity against E. coli infection. © 1987.

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Iida, J., Une, T., Ishihara, C., Nishimura, K., Tokura, S., Mizukoshi, N., & Azuma, I. (1987). Stimulation of non-specific host resistance against Sendai virus and Escherichia coli infections by chitin derivatives in mice. Vaccine, 5(4), 270–274. https://doi.org/10.1016/0264-410X(87)90150-2

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