Structural characterization and anti-tumor activity of a novel heteropolysaccharide isolated from taxus yunnanensis

  • Yin Y
  • Yu R
  • Yang W
 et al. 
  • 5


    Mendeley users who have this article in their library.
  • 16


    Citations of this article.


TMP70S-1, a novel water-soluble polysaccharide with molecular weight of 17.37 kDa, was isolated from Taxus yunnanensis Cheng et L. K. Fu by a combination of ion-exchange chromatography on the DEAE-Cellulose 52 and gel permeation on Sephacryl S-100. It was constituted of d-rhamnose, d-galactose, d-xylose in the molar ration of 2.01:6.74:1. According to total hydrolysis, periodate oxidation, methylation analysis, in combination with NMR studies, the predicted structure of TMP70S-1 was shown as follows: The in vitro anti-tumor experiments of Hela and HT1080 cells by the method of MTT showed that TMP70S-1 could have a potent possibility for the selection as an anti-tumor agent. © 2010 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • Anti-tumor activity
  • Plant polysaccharide
  • Structural analysis
  • Taxus yunnanensis

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free