Synthetic studies towards the diterpene natural product FCRR toxin have been undertaken. An intermolecular [5+2] oxidopyrylium-alkene cycloaddition reaction was employed to construct the 7-5-6 tricyclic framework. The reaction proceeded with very high regio- and stereoselectivity and the bridging ether was reductively cleaved to unmask the carbocycle. © 2003 Elsevier Ltd. All rights reserved.
Murali Krishna, U., & Trivedi, G. K. (2004). Studies towards the synthesis of FCRR toxin: An expeditious entry into 7-5-6 ring systems via [5+2] oxidopyrylium-alkene cycloaddition. Tetrahedron Letters, 45(2), 257–259. https://doi.org/10.1016/j.tetlet.2003.10.185