Surface plasmon studies of specific recognition reactions at self-assembled monolayers on gold

  • Schmitt F
  • Häussling L
  • Ringsdorf H
 et al. 
  • 4


    Mendeley users who have this article in their library.
  • 37


    Citations of this article.


Specific recognition reactions of proteins at functionalized interfaces were observed with plasmon surface polariton (PSP) spectroscopy. This optical method offers a vertical resolution of about 0.2 nm in aqueous media. Different types of receptor surfaces were prepared, either by self-assembly of biotinylated alkane thiols or by specific adsorption of streptavidin monolayers. The corresponding substrates were streptavidin and a biotinylated monoclonal antibody. Their binding properties are inversely related to the packing density of the receptors. A good accessibility is only given in the case of a "diluted" presentation of the receptors at the interface. Both binding site and diffusion limited adsorption have been observed. © 1992.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • F. J. Schmitt

  • L. Häussling

  • H. Ringsdorf

  • W. Knoll

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free