Synthesis of 3-alkylidene-piperidin-4-ones via one-pot cascade transylidation-olefination

2Citations
Citations of this article
5Readers
Mendeley users who have this article in their library.
Get full text

Abstract

3-Alkylidene-piperidin-4-ones with diverse C-5 substitution patterns are synthesized via a one-pot cascade transylidation-olefination sequence. Tributylphosphorus ylides show distinct higher reactivity as compared to triphenyl analogs. t-Butanol is the solvent of choice for transylidation, while the Wittig olefination of aliphatic aldehydes requires MeCN as the solvent. © 2009 Elsevier Ltd. All rights reserved.

Cite

CITATION STYLE

APA

Wang, B. (2009). Synthesis of 3-alkylidene-piperidin-4-ones via one-pot cascade transylidation-olefination. Tetrahedron Letters, 50(21), 2487–2489. https://doi.org/10.1016/j.tetlet.2009.03.023

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free