Synthesis of C-3 alkyl analogs of cocaine

  • Deng S
  • Huang D
  • Landry D
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Abstract

The first general stereocontrolled approach to C-3 alkyl analogs of cocaine is described. The route utilized versatile intermediates 2β-hydroxymethyl-3α-cyanotropane and 2β-hydroxymethyl-3β-cyanotropane. © 2001 Elsevier Science Ltd. All rights reserved.

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Authors

  • Shi Xian Deng

  • Dan Wen Huang

  • Donald W. Landry

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