Synthesis, NMR and structure of oligonucleotide phosphorodithioates

  • Piotto M
  • Granger J
  • Cho Y
 et al. 
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Thiophosphoramidite as well as thiophosphoramidate chemistry has been used to prepare dithiophosphate analogues of oligonucleotides. The1H and13P resonances of the 3′-thymidine phosphorodithioate decamer d(CGCTpS-2TpS-2AAGCG) were assigned by two-dimensional NMR and the solution structure determined. © 1991.

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  • Martial E. Piotto

  • Jill Nelson Granger

  • Yesun Cho

  • Nasser Farschtschi

  • David G. Gorenstein

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