Synthesis of a salbutamol dimer

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Abstract

First synthesis of the diastereomeric mixture of Salbutamol dimer (2) is described. The synthesis provides access to multi-gram quantities of 2 for reference supplies and further analytical and toxicology investigations. It also confirmed the proposed structure by comparison to authentic sample. © 2002 Elsevier Science Ltd. All rights reserved.

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Haddad, N., Xu, Y., Baron, J. A., & Yee, N. K. (2002). Synthesis of a salbutamol dimer. Tetrahedron Letters, 43(7), 1135–1137. https://doi.org/10.1016/S0040-4039(01)02354-1

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