Synthesis of statine and its analogues by homogeneous asymmetric hydrogenation

  • Nishi T
  • Kitamura M
  • Ohkuma T
 et al. 
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Abstract

Diastereoselective hydrogenation of N-protected γ-amino β-keto esters catalyzed by BINAP--Ru(II) complexes provides an efficient entry to the statine series with high enantiomeric purities. © 1988.

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