A theoretical description of phase diagrams for nonideal lipid mixtures is presented. The phase diagrams in this model are constructed by a quasi-chemical approach for the calculations of enthalpies of the regular solutions and by van der Waals attractive energy of lipids which described the degree of non-ideality in the solid and fluid phases. The results of theoretical calculations of phase diagrams for dimyristoyl phosphatidylcholine/dipalmitoyl phosphatidylcholine, dimyristoyl phosphatidylcholine/distearoyl phosphatidylcholine, and dipalmitoyl phosphatidylcholine/distearoyl phosphatidylcholine mixtures are in good agreement with experimental data. © 1980, All rights reserved.
Cheng, W. H. (1980). A theoretical description of phase diagrams for nonideal lipid mixtures. Biochimica et Biophysica Acta - Biomembranes, 600(2), 358–366. https://doi.org/10.1016/0005-2736(80)90439-3