A theoretical description of phase diagrams for nonideal lipid mixtures

Abstract

A theoretical description of phase diagrams for nonideal lipid mixtures is presented. The phase diagrams in this model are constructed by a quasi-chemical approach for the calculations of enthalpies of the regular solutions and by van der Waals attractive energy of lipids which described the degree of non-ideality in the solid and fluid phases. The results of theoretical calculations of phase diagrams for dimyristoyl phosphatidylcholine/dipalmitoyl phosphatidylcholine, dimyristoyl phosphatidylcholine/distearoyl phosphatidylcholine, and dipalmitoyl phosphatidylcholine/distearoyl phosphatidylcholine mixtures are in good agreement with experimental data. © 1980, All rights reserved.