Transformation of chick embryo fibroblasts by reticuloendotheliosis virus

  • Franklin R
  • Kang C
  • Min-Min Wan K
 et al. 
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Abstract

A strain of reticuloendotheliosis virus-infected chicken embryo fibroblasts has been isolated and found to be transformed by the following criteria: (1) altered morphology, (2) increased cell density, (3) increased passage capability, (4) growth in soft agar, (5) increased uptake of 2-deoxy-D-glucose, and (6) tumorigenicity. Detectable avian leukosis-sarcoma viruses are not produced by these cells. © 1977.

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Authors

  • Ray B. Franklin

  • Chil Yong Kang

  • Katherine Min-Min Wan

  • Henry R. Bose

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