Uncoupling of CA3 pyramidal neurons by propionate

  • MacVicar B
  • Jahnsen H
  • 5


    Mendeley users who have this article in their library.
  • 26


    Citations of this article.


The influence of cytoplasmic acidification on dye-coupling between CA3 pyramidal neurons was examined by Lucifer yellow injections in guinea pig hippocampal brain slice. Neurons were believed to be acidified by exposure to 100 mM propionate. Dye-coupling was reduced significantly to 6% (n = 35) in propionate versus 28% (n = 39) in control solution (P < 2 %). Propionate may be a useful tool for experimental manipulation of coupling in the mammalian CNS. © 1985.

Author-supplied keywords

  • electrotonic coupling
  • hippocampus pyramidal neurons
  • propionate
  • uncoupling

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free