An in vivo demonstration of the bicarbonate ion pump of rabbit corneal endothelium

  • Mayes K
  • Hodson S
  • 3


    Mendeley users who have this article in their library.
  • 14


    Citations of this article.


The bicarbonate concentration in the stromal fluid of rabbit corneas in vivo is depressed by more than 50% of its level in the aqueous humour. After allowing for ion-exchange effects, electrochemical potential effects, binding phenomena, compartmentalization and pH effects, it is concluded that most of the depression is caused by an active efflux of bicarbonate ions out of the stroma. Simple flux analysis suggests that the magnitude of the active bicarbonate efflux equals that previously measured to pass across the endothelium in the in vitro preparation. © 1979.

Author-supplied keywords

  • bicarbonate
  • corneal endothelium
  • ion pump

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Kenneth R. Mayes

  • Stuart Hodson

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free