I earned my PhD in Neuroscience in 2003 at Paris VI, while working with Francis Crépel and Hervé Daniel on synaptic plasticity using patch-clamp recordings on cerebellar slices. In my dissertation, I described for the first time, several forms of synaptic plasticity between stellate cells and parallels fibers. Then, I joined Jean Rossier’s laboratory at the ESPCI ParisTech, as a postdoctoral fellow, to study the neurovascular coupling within the cerebellum. I demonstrated that cerebellar stellate and Purkinje cells dilate and constrict, respectively, neighboring blood vessels. In 2006, I got a researcher position at the INSERM. Combining patch-clamp, RT-PCR, infrared videomicroscopy and Neurolucida reconstructions, I characterized the roles of different interneuron subpopulations in the neurovascular coupling of the mouse somatosensory cortex. Currently, I am now studying the role of metabolism on neuronal activity and blood vessel tonus within the ventrolateral preoptic nucleus (VLPO), the structure responsible for the onset and maintenance of the slow-wave sleep.
College de France Center for Interdisciplinary Research in Biology