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Brad Sleebs

  • PhD
  • Laboratory Head
  • Walter and Eliza Hall Institute of Medical Research
  • 16h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 893CitationsNumber of citations received by Brad's publications. Updated daily.

Research interests

MalariaInfecticous DiseaseDrug DesignMedicinal ChemistryCancer

About

Our laboratory applies chemical biology and medical chemistry techniques to investigate and better understand biological processes that cause disease progression. Our goal is to translate the basic understanding of biological mechanisms into new therapeutics to treat cancers and infectious diseases, such as malaria.

Co-authors (192)

Publications (5)

  • Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

    • Gilson P
    • Tan C
    • Jarman K
    • et al.
    N/AReaders
    7Citations
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  • Discovery of a potent and selective BCL-X<inf>L</inf>inhibitor with in vivo activity

    • Tao Z
    • Hasvold L
    • Wang L
    • et al.
    N/AReaders
    71Citations
    Get full text
  • Structure-guided rescaffolding of selective antagonists of BCL-X<inf>L</inf>

    • Koehler M
    • Bergeron P
    • Choo E
    • et al.
    N/AReaders
    11Citations
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  • Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-X<inf>L</inf>

    • Sleebs B
    • Kersten W
    • Kulasegaram S
    • et al.
    N/AReaders
    30Citations
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  • Structure-guided design of a selective BCL-X<inf>L</inf>inhibitor

    • Lessene G
    • Czabotar P
    • Sleebs B
    • et al.
    N/AReaders
    146Citations
    Get full text

Professional experience

Laboratory Head

The Walter and Eliza Hall Institute of Medical Research

January 2005 - Present

Education

PhD BSc

LaTrobe University

January 1997 - December 2004(8 years)