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Brian Chen

  • Ph.D.
  • Assistant Professor
  • Department of Computer Science and Engineering, Lehigh University
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Readers

Number of times these publications have been added to libraries on Mendeley.
16

Publications

Number of items in this person’s My Publications folder on Mendeley.

Research Interests

Structural Bioinformatics Computational and Structural Biology

Followers (12)

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Following (13)

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About

I am an assistant professor in the Department of Computer Science and Engineering within the P. C. Rossin College of Engineering and Applied Sciences at Lehigh University. My research focuses primarily on structural bioinformatics.

I was a postdoctoral research scientist at Barry Honig's Lab at the Howard Hughes Medical Institute, the Department of Biochemistry and Molecular Biophysics, and the Center for Computational Biology and Bioinformatics at Columbia University. At Columbia, I gained considerable exposure to research in structural biology, biophysics, and protein crystallography.

I earned a Ph.D. from Rice University's Department of Computer Science for my work on protein function annotation. My advisor was Dr. Lydia Kavraki. While at Rice, I had the pleasure to learn quite a bit about structural bioinformatics, robotics, graphics, and distributed systems.

I received a B.A. in Mathematics and a B.A. in Computer Science from Rutgers College at Rutgers University, the State University of New Jersey, in 2000. While at Rutgers, I had the opportunity to do a summer project with János Komlós, and some signal processing with William Craelius.

Publications

MarkUs: a server to navigate sequence-structure-function space.

Fischer M, Zhang Q, Dey F, Chen B, Honig B, Petrey D

Nucleic acids research (2011)

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Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction

Bryant D, Moll M, Chen B, Fofanov V, Kavraki L

BMC bioinformatics (2010)

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Mapping of ligand-binding cavities in proteins.

Andersson C, Chen B, Linusson A

Proteins: Structure, Function, and Bioinformatics (2010)

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Multivariate assessment of virtual screening experiments

Andersson C, Chen B, Linusson A

Journal of Chemometrics (2010)

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VASP: A Volumetric Analysis of Surface Properties Yields Insights into Protein-Ligand Binding Specificity

Chen B, Honig B

PLoS Computational Biology (2010)

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Professional experience

Assistant Professor

Department of Computer Science and Engineering, Lehigh University

August 2010 - Present

Postdoctoral Research Scientist

Howard Hughes Medical Institute, Dept. of Biochemistry and Molecular Biophysics, Center for Computational Biology and Bioinformatics, Columbia University

December 2006 - July 2010 (3 years 7 months)

Research Assistant

Rice University Department of Computer Science

August 2000 - November 2006 (6 years 3 months)

Education history

Rice University

Ph.D.

August 2000 - November 2006 (6 years 3 months)

Rutgers University Rutgers Business School

Computer Science and Mathematics

August 1996 - May 2000 (3 years 9 months)