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Christian Speck

  • Group Head
  • Imperial College London
  • 10PublicationsNumber of items in Christian's My Publications folder on Mendeley.

Research interests

DNA Replication

Publications (5)

  • An ORC/Cdc6/MCM2-7 Complex Is Formed in a Multistep Reaction to Serve as a Platform for MCM Double-Hexamer Assembly

    • Fernández-Cid A
    • Riera A
    • Tognetti S
    • et al.
    N/AReaders
    N/ACitations
  • Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

    • Sun J
    • Evrin C
    • Samel S
    • et al.
    N/AReaders
    N/ACitations
    Get full text
  • In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.

    • Evrin C
    • Fernández-Cid A
    • Zech J
    • et al.
    N/AReaders
    N/ACitations
    Get full text
  • The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.

    • Evrin C
    • Fernández-Cid A
    • Riera A
    • et al.
    N/AReaders
    N/ACitations
    Get full text
  • A top-down view on DNA replication and recombination from 9,000 feet above sea level

    • Johansson E
    • Speck C
    • Chabes A
    N/AReaders
    N/ACitations
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Professional experience

Group Head

Imperial College London

October 2006 - Present