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Daniel Ortwine

  • BS
  • Principal Scientist
  • Genentech Inc
  • 29h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 2722CitationsNumber of citations received by Daniel's publications. Updated daily.

Other IDs

Research interests

Computational chemistry

Co-authors (514)

  • Vickie Tsui

Publications (5)

  • Computational Support of Medicinal Chemistry in Industrial Settings

    • Ortwine D
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  • Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N -([1,2,4]Triazolo[4,3- a ]pyridin-3-yl)methane-sulfonamides as Potent and Selective h Na V 1.7 Inhibitors for the Treatment of Pain

    • Focken T
    • Chowdhury S
    • Zenova A
    • et al.
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  • Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton’s Tyrosine Kinase Inhibitor in Early Clinical Development

    • Crawford J
    • Johnson A
    • Misner D
    • et al.
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  • Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors

    • Chernov-Rogan T
    • Li T
    • Lu G
    • et al.
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  • Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

    • Liang J
    • Zhang B
    • Labadie S
    • et al.
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Professional experience

Principal Scientist

Genentech

August 2007 - Present

Research Fellow

Pfizer

September 1976 - April 2007(31 years)