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Dario Corrada

  • Ph.D. in Molecular Medicine
  • PostDoc
  • Università degli Studi di Milano - Bicocca, Milan, Italy
  • 5h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 133CitationsNumber of citations received by Dario's publications. Updated daily.

Other IDs

Research interests

elastic network modelsmolecular dynamicsantibodies

About

I was born in Monza (Italy) on Feb 7th 1980. In 2006, I got my M. Sc. in Pharmaceutical Biotechnology at Università degli Studi di Milano. In 2007, I worked as research fellow at the Institute of Biomedical Technologies (ITB-CNR, http://www.itb.cnr.it/web/bioinformatics). My project consisted in the development and validation of automated tools for comparative modelling and threading; in particular, I have collaborated with the Parco Tecnologico Padano (http://www.tecnoparco.org/) to the definition of a homology model of the sialoadhesin Siglec-1, for its involvement in the onset of Porcine Respiratory and Reproductive Syndrome. In 2009 I have attended at RGASP project (http://www.gencodegenes.org/rgasp) which aims to assess the algorithms for automatic analysis of data from NGS platforms and to develop new methods for mapping RNASeq data to genome assemblies. In 2010 I got my PhD in Molecular Medicine at Università degli Studi di Milano, with a thesys on the bioinformatic analysis of genome-wide microRNA target prediction data and functional characterization. My work was focused on cardiac hypertrophy, defining the pattern of genes which depends on the expression deregulation of miR-199 and miR-214. In 2011 I joined Dr. Colombo’s group at ICRM-CNR. My current research interests focus on the definition of those descriptors that characterize conformational change events related to the formation of antibody::antigen complexes, through the application of extensive molecular dynamics (MD) simulations.

Co-authors (29)

Publications (5)

  • Molecular modeling of the AhR structure and interactions can shed light on ligand-dependent activation and transformation mechanisms

    • Bonati L
    • Corrada D
    • Tagliabue S
    • et al.
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  • Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization.

    • Corrada D
    • Denison M
    • Bonati L
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  • Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation.

    • Corrada D
    • Soshilov A
    • Denison M
    • et al.
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  • Prediction of Antigenic B and T Cell Epitopes via Energy Decomposition Analysis: Description of the Web-Based Prediction Tool BEPPE.

    • Peri C
    • Solé O
    • Corrada D
    • et al.
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  • Energetic and dynamic aspects of the affinity maturation process: characterizing improved variants from the bevacizumab antibody with molecular simulations.

    • Corrada D
    • Colombo G
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Professional experience

PostDoc

Università degli Studi di Milano - Bicocca, Milan, Italy

September 2013 - Present

PostDoc

CNR - Institute of Chemistry of Molecular Recognition

June 2011 - June 2013(2 years)

Ph. D. fellowship

CNR - Institute for Biomedical Technologies

November 2007 - October 2010(3 years)

Education

M.Sc. Pharmaceutical Biotechnology

Department of Pharmacological Sciences, Università degli Studi di Milano

October 1999 - October 2006(7 years)