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David Briggs

  • PhD Protein Crystallography
  • Post Doc
  • Imperial College London
  • --

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  • 12

    Publications

    Number of items in this person’s My Publications folder on Mendeley.

Research interests

Proteoglycans Structural Biology Interaction analysis Crystallography SAXS

About

A protein crystallographer and biophysicist with training in small angle X-ray scattering and many different interaction analysis techniques, such as isothermal titration calorimetry and surface plasmon resonance. I am currently employed at Imperial College London, in the group of Prof Erhard Hohenester, using these skills to investigate the Laminin family of extracellular matrix proteins.

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Following (12)

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Publications

Crystallographic analysis of the laminin β2 short arm reveals how the LF domain is inserted into a regular array of LE domains

  • Pulido D
  • Briggs D
  • Hua J
  • Hohenester E
Matrix Biology (2016)
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J. Biol. Chem.-2013-Baranova-29642-53

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Structural basis of laminin binding to the LARGELARGE glycans on dystroglycan

  • Briggs D
  • Yoshida-Moriguchi T
  • Zheng T
  • Venzke D
  • Anderson M
  • Strazzulli A
  • Moracci M
  • Yu L
  • Hohenester E
  • Campbell K
  • --

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A Refined Model for the TSG-6 Link Module in Complex with Hyaluronan USE OF DEFINED OLIGOSACCHARIDES TO PROBE STRUCTURE AND FUNCTION *

  • Higman V
  • Briggs D
  • Mahoney D
  • Blundell C
  • Sattelle B
  • Dyer D
  • Green D
  • Deangelis P
  • Almond A
  • Milner C
  • Day A
  • --

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Incorporation of Pentraxin 3 into Hyaluronan Matrices Is Tightly Regulated and Promotes Matrix Cross-linking

  • Baranova N
  • Inforzato A
  • Briggs D
  • Tilakaratna V
  • Enghild J
  • Thakar D
  • Milner C
  • Day A
  • Richter R
Published JBC Papers in Press (2014)
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Professional experience

Post Doc

Imperial College London

August 2014 - Present

Post Doc

University of Manchester Faculty of Life Sciences

November 2006 - July 2014 (8 years)

Post Doc

Cancer Research UK, London Research Institute

April 2004 - October 2006 (3 years)

Education history

Birkbeck College, University of London

PhD Protein Crystallography

September 2001 - April 2004 (3 years)

Birkbeck College, University of London

MRes Structural Biology

September 2000 - September 2001 (a year)

University of Birmingham

BSc Biochemistry and Biotechnology

September 1996 - June 2000 (4 years)