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David MacIntyre

  • PhD
  • Imperial College London
  • 21h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 1589CitationsNumber of citations received by David's publications. Updated daily.


Dr David MacIntyre’s research investigates the role of inflammation in the onset of term and preterm human labour. He is particularly interested in understanding the implications of the vaginal microbiome in preterm premature rupture of membranes (PPROM), which is also known as when a woman’s waters break early during her pregnancy. His research team approaches this using both classical biochemistry methods as well as a “systems” approach where data acquired from genomic, transcriptomic and metabonomic platforms are integrated and modelled to investigate the interaction between vaginal microbiota and the maternal host. It is hoped that will lead to improved diagnostic and predictive tools that will assist in patient stratification and ultimately, improved pregnancy outcomes.

Recent publications

  • Progesterone, the maternal immune system and the onset of parturition in the mouse.

    • Edey L
    • Georgiou H
    • O’Dea K
    • et al.
  • Brown and white adipose tissues: Intrinsic differences in gene expression and response to cold exposure in mice

    • Rosell M
    • Kaforou M
    • Frontini A
    • et al.

Professional experience

Imperial College London

Co-authors (179)

  • Simon Waddington
  • shima jalalian sedaghati