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Dimitrios Vatakis

  • University of California Los Angeles
  • 13h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 442CitationsNumber of citations received by Dimitrios's publications. Updated daily.

Other IDs

Research interests

CancerImmunologyHIVDrug Abuse

About

Our major research interests aim to (i) understand why distinct cell types are differentially susceptible to HIV infection and how this impacts HIV replication and disease progression and (ii) examine the influence of chronic disease on immune function using humanized mouse models. We are interested in the nature of the block in quiescent CD4 T cells to HIV infection, the role viral factors and/or target cell physiology have on the susceptibility to infection and progression of the viral life cycle, and to understand the effect that chronic infection and/or disease have on immune function using humanized mouse models. These studies will provide a novel insight that defines the fine balance of virus-host interactions and ultimately develop novel therapies to target pathogens and prevent spread of infection.

Co-authors (91)

  • Iasonas Kokkinos
  • Argiro Vatakis

Publications (5)

  • HIV integration and the establishment of latency in CCL19-treated resting CD4<sup>+</sup>T cells require activation of NF-ΚB

    • Saleh S
    • Lu H
    • Evans V
    • et al.
    N/AReaders
    8Citations
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  • Engineering cellular resistance to HIV-1 infection in vivo using a dual therapeutic lentiviral vector

    • Burke B
    • Levin B
    • Zhang J
    • et al.
    N/AReaders
    20Citations
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  • Quiescent CD4<sup>+</sup>T cells inhibit multiple stages of HIV infection

    • Zack J
    • Vatakis D
    N/AReaders
    0Citations
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  • Using the BLT humanized mouse as a stem cell based gene therapy tumor model.

    • Vatakis D
    • Bristol G
    • Kim S
    • et al.
    N/AReaders
    11Citations
  • Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells

    • Vatakis D
    • Koya R
    • Nixon C
    • et al.
    N/AReaders
    50Citations
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Professional experience

University of California - Los Angeles

Education history

PhD

University of Southern California

August 1998 - August 2003(5 years)