Elia Mario Biganzoli. Born 18 April 1966, Tradate (VA). Faculty of Sciences-University of Milano, degree in Biology 1988 Summa Cum Laude. Post-graduate degree, PhD in Medical Statistics in 1994-1996 at University, Milan, Summa Cum Laude. 1989-94 Research fellow, Institute of Pharmacology, Faculty of Sciences - Giovanni Lorenzini Foundation, Milano. 1989-94 Consultant Researcher for drug discovery, assay development, high throughput screening and data analysis, at the Lepetit Research Center (Marion Merrel Dow, USA), Gerenzano (VA). 1995 - Senior Biostatistician, Unit of Medical Statistics and Biometry, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan. 2000 – 2007 Contract Professor of Biostatistics, Faculty of Statistics, University of Milano-Bicocca. 2000-2004 Executive Committee of the International Society for Clinical Biostatistics. 2004 – 2008 Task Force Leader Evaluation & Benchmarking, BIOPATTERN Network of Excellence FP6 project:" Computational Intelligence for Biopattern Analysis in Support of eHealthcare". 2005–2009 Board of the International Biometric Society, Italian Region – 2007- Associate Professor in Medical Statistics at the Faculty of Medicine of the University of Milan, 2009 Cofounder of the IEEE Neural Network Society Special Interest Group Biopattern. 2014-Qualified as Full Professor in Medical Statistics.
He was responsible and participated to national and international projects with Associazione Italiana per la Ricerca sul Cancro, National Research Council-Polish Academy of Sciences, Italian Ministry of Health, Italian Ministry of the University and Research, European Commission. His main research fields concern statistical methods for survival analysis and biological assay development. He participated in the planning of diagnostic and prognostic studies in cancer, cardiovascular diseases, rheumatology, hematology and the analysis of their results with special interest on molecular biomarkers and bioprofiles. He developed statistical approaches for the extension of generalized linear models with artificial neural networks and splines for the flexible analysis of censored survival data. His main research focus with his group was to join biostatistics with biomedical informatics through multivariate analysis and pattern recognition approaches in oncology. Biostatistical consultant for the application of bioinformatics in drug discovery and development in industrial biotechnology and pharmaceutical research (Nerviano-MS, Italy; Themis-ICTA, France).
He is author of more than 150 scientific full publications on international journals, books, technical reports and international conference proceedings. He participated with his research group on Biostatistics for Bionformatics and Clinical Translational Research (BBCTR) of the Fondazione IRCCS Istituto Nazionale dei Tumori (INT) and University of Milano, to National and European consortia such as the (ISS-ACC) RNBIO project National Network for Bioinformatics, the FP6 Network of Excellence BIOPATTERN (FP6-2002-IST-1-N° 508803) involving more than 30 EU centers focused on biomedical informatics and the FP6 BIOPTRAIN Marie Curie Early Stage Training Fellowship. In particular, he was the leader of the Biostatistics for Bioinformatics Group of the RNBIO ISS ACC Oncology Bioinformatics Network. He is co-organiser of the EU Lifelong Learning Programme Erasmus Intensive Programme (IP) 2010-2013: “Interdisciplinary Approaches to Microarray Data Analysis” with the universities of Salerno, Napoli, Warwick and Helsinki. He was panel discussant with FDA delegates in the 3rd International Symposium on Integrated Biomarkers in Cardiovascular Diseases (Seattle, WA, USA / July 9-11, 2008). He was the main organizer of the 8th International Meeting on Computational Intelligence for Bioinformatics and Biostatistics CIBB 2011 (Gargnano del Garda, BS Italy / June 30-July 2, 2011). He is in the Steering Committee of CIBB conferences and Invited Key-Note Speaker in CIBB 2012 in Houston TX at The Methodist Hospital. He contributed to the organization of CIBB 2014 in Cambridge UK.
Dynamics of the hazard for distant metastases after ipsilateral breast tumor recurrence according to estrogen receptor status: An analysis of 2851 patients