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fabio francini

  • Universita degli Studi di Firenze
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The research field from 2000 was extended to electrophysiological researches on ionic channels activated by voltage and stretch (Stretch activated channel, SAC) in myoblasts, cardiomyocytes, staminal and mesenchymal cells. In these researches it was evaluated the differentiation processes operated by growth factor (sphyngosine 1-phophate, relaxin, tiroxin hormon,….), by differentiation medium composition and by cocultures of different cell lines. It was found that staminal and mesenchymal cells may differentiate in different phenotype cell line and that the cytoskeleton is involved in regulating cell differentiation.

Recent publications

  • Cortical and spinal conditioned media modify the inward ion currents and excitability and promote differentiation of human striatal primordium

    • Idrizaj E
    • Sarchielli E
    • Morelli A
    • et al.
  • Sphingosine 1-Phosphate Induces Cell Contraction Via Calcium-Independent/Rho-Dependent Pathways in Undifferentiated Skeletal Muscle Cells

    • Formigli L
    • Meacci E
    • Vassalli M
    • et al.

Professional experience

Universita degli Studi di Firenze


Sperimental and clinic medicine, section physiology

university of Florence

August 1960 - March 1967(7 years)

Co-authors (171)

  • Michaela Luconi
  • Antonio Augusto Franco Garcia
  • Massimo Vassalli