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Francisco Adasme

  • Bioinformatics Engineer
  • Undergraduate
  • Universidad de Talca
  • 3Followers
  • 3Following

About

Born and raised in Talca, Chile I became a bioinformatics engineering student at Universidad de Talca, Chile on 2006. I like informatic stuff very much, and I consider myself a gamer. Also, I have developed basic skills in web design and programming in multiple languages through the last five years. Currently, I'm developing an automatic profiling system for detecting certain patterns in eletrical penetration graph output (EPG - technique used by biologists to study the interaction of insects such as aphids and leafhoppers with plants). Also, I'm studying how electrostatic interactions (e.g. cation-pi and hydrogen bonds) can contribute to protein-ligand interactions and if they can rationalize drug binding behavior in nicotinic acetylcholine receptors (nAChRs). For this, I use theoretical methods such as homology modeling, molecular dynamics, docking techniques and the hybrid approach QM/MM to generate structural models (a4b2 and a7 nAChR subtypes) and obtain accurate binding energies for several known ligands. For such work, I'm using Schrodinger suite which includes Glide, Desmond and Qsite.

Professional experience

Undergraduate

Universidad de Talca

March 2006 - Present

Education

Undergraduate

Universidad de Talca

March 2006 - Present

Followers (3)

Following (3)