Gabriele Toietta

Research Interests

regenerative medicine cell therapy gene therapy

Publications

A CREB-Sirt1-Hes1 circuitry mediates neural stem cell response to glucose availability

Fusco S, Leone L, Barbati S, Samengo D, Piacentini R, Maulucci G, Toietta G, Spinelli M, McBurney M, Pani G, Grassi C

Cell Reports (2016)

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Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2- ∆ e8 isoform

Di Rocco G, Verdina A, Gatti V, Virdia I, Toietta G, Todaro M, Stassi G, Soddu S

Oncotarget (2015)

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Adipose tissue: from energy reservoir to a source of cells for epithelial tissue engineering

Trivisonno A, Abecassis M, Monti M, Toietta G, Bachir A

Stem Cells in Aesthetic … (2014)

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Effects of the Olive-Derived Polyphenol Oleuropein on Human Health

Barbaro B, Toietta G, Maggio R, Arciello M, Tarocchi M, Galli A, Balsano C

International Journal of Molecular Sciences (2014)

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Harvest of superficial layers of fat with a microcannula and isolation of adipose tissue-derived stromal and vascular cells.

Trivisonno A, Di Rocco G, Cannistra C, Finocchi V, Torres Farr S, Monti M, Toietta G

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery (2014)

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Diabetes impairs adipose tissue-derived stem cell function and efficiency in promoting wound healing

Cianfarani F, Toietta G, Di Rocco G, Cesareo E, Zambruno G, Odorisio T

Wound Repair and Regeneration (2013)

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A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction

Fusco S, Ripoli C, Podda M, Ranieri S, Leone L, Toietta G, McBurney M, Schutz G, Riccio A, Grassi C, Galeotti T, Pani G

Proceedings of the National Academy of Sciences (2012)

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Analysis of biodistribution and engraftment into the liver of genetically-modified mesenchymal stromal cells derived from adipose tissue.

Di Rocco G, Gentile A, Antonini A, Truffa S, Piaggio G, Capogrossi M, Toietta G

Cell transplantation (2012)

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Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals.

Goeman F, Manni I, Artuso S, Ramachandran B, Toietta G, Bossi G, Rando G, Cencioni C, Germoni S, Straino S, Capogrossi M, Bacchetti S, Maggi A, Sacchi A, Ciana P, Piaggio G

Molecular biology of the cell (2012)

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Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process.

Avitabile D, Crespi A, Brioschi C, Parente V, Toietta G, Devanna P, Baruscotti M, Truffa S, Scavone A, Rusconi F, Biondi A, D'Alessandra Y, Vigna E, Difrancesco D, Pesce M, Capogrossi M, Barbuti A

American journal of physiology. Heart and circulatory physiology (2011)

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Human epicardium-derived cells fuse with high efficiency with skeletal myotubes and differentiate toward the skeletal muscle phenotype: a comparison study with stromal and endothelial cells.

Gentile A, Toietta G, Pazzano V, Tsiopoulos V, Giglio A, Crea F, Pompilio G, Capogrossi M, Di Rocco G

Molecular Biology of the Cell (2011)

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The FGF-2-Derived Peptide FREG Inhibits Melanoma Growth In Vitro and In Vivo.

Aguzzi M, Faraone D, D'Arcangelo D, De Marchis F, Toietta G, Ribatti D, Parazzoli A, Colombo P, Capogrossi M, Facchiano A

Molecular therapy : the journal of the American Society of Gene Therapy (2011)

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Enhanced healing of diabetic wounds by topical administration of adipose tissue-derived stromal cells overexpressing stromal-derived factor-1: biodistribution and engraftment analysis by bioluminescent imaging.

Di Rocco G, Gentile A, Antonini A, Ceradini F, Wu J, Capogrossi M, Toietta G

Stem Cells International (2010)

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Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage.

Panieri E, Toietta G, Mele M, Labate V, Ranieri S, Fusco S, Tesori V, Antonini A, Maulucci G, De Spirito M, Galeotti T, Pani G

Aging (2010)

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Role of HIF-1alpha in proton-mediated CXCR4 down-regulation in endothelial cells.

Melchionna R, Romani M, Ambrosino V, D'Arcangelo D, Cencioni C, Porcelli D, Toietta G, Truffa S, Gaetano C, Mangoni A, Pozzoli O, Cappuzzello C, Capogrossi M, Napolitano M

Cardiovascular Research (2010)

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Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo.

Faraone D, Aguzzi M, Toietta G, Facchiano A, Facchiano F, Magenta A, Martelli F, Truffa S, Cesareo E, Ribatti D, Capogrossi M, Facchiano A

Neoplasia New York Ny (2009)

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Spontaneous myogenic differentiation of Flk-1-positive cells from adult pancreas and other nonmuscle tissues

Rocco G, Tritarelli A, Toietta G, Gatto I, Iachininoto M, Pagani F, Mangoni A, Straino S, Capogrossi M, F P, A M, S S, Capogrossi M C

American Journal of Physiology Cell Physiology (2008)

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Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy.

Severino A, Campioni M, Straino S, Salloum F, Schmidt N, Herbrand U, Frede S, Toietta G, Di Rocco G, Bussani R, Silvestri F, Piro M, Liuzzo G, Biasucci L, Mellone P, Feroce F, Capogrossi M, Baldi F, Fandrey J, Ehrmann M, Crea F, Abbate A, Baldi A

Journal of the American College of Cardiology (2007)

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Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors.

Mane V, Toietta G, McCormack W, Conde I, Clarke C, Palmer D, Finegold M, Pastore L, Ng P, Lopez J, Lee B

Gene Therapy (2006)

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Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

Toietta G, Mane Viraj P, Norona Wilma S, Finegold Milton J, Ng P, McDonagh Antony F, Beaudet Arthur L, Lee B

Proceedings of the National Academy of Sciences of the United States of America (2005)

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PEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile.

Croyle M, Le H, Linse K, Cerullo V, Toietta G, Beaudet A, Pastore L

Gene Therapy (2005)

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Adenovirus vectors targeting alphaV integrin or heparan sulfate receptors display different distribution of transgene activity after intramuscular injection.

Cirielli C, Serino F, Straino S, Toietta G, Abeni D, Ventoruzzo G, Orlando G, Mazzanti P, Melillo G, Whickham T, Kovesdi I, Biglioli P, Gaetano C, Capogrossi M

Journal of Gene Medicine (2004)

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Reduced inflammation and improved airway expression using helper-dependent adenoviral vectors with a K18 promoter.

Toietta G, Koehler D, Finegold M, Lee B, Hu J, Beaudet A

Molecular therapy the journal of the American Society of Gene Therapy (2003)

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Generation of helper-dependent adenoviral vectors by homologous recombination.

Toietta G, Pastore L, Cerullo V, Finegold M, Beaudet A, Lee B

Molecular therapy the journal of the American Society of Gene Therapy (2002)

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Various cells retrovirally transduced with N-acetylgalactosoamine-6-sulfate sulfatase correct Morquio skin fibroblasts in vitro.

Toietta G, Severini G, Traversari C, Tomatsu S, Sukegawa K, Fukuda S, Kondo N, Tortora P, Bordignon C

Human Gene Therapy (2001)

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Biochemical and structural analysis of missense mutations in N-acetylgalactosamine-6-sulfate sulfatase causing mucopolysaccharidosis IVA phenotypes.

Sukegawa K, Nakamura H, Kato Z, Tomatsu S, Montaño A, Fukao T, Toietta G, Tortora P, Orii T, Kondo N

Human Molecular Genetics (2000)

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Molecular cloning, nucleotide sequence, and expression of a carboxypeptidase-encoding gene from the archaebacterium Sulfolobus solfataricus.

Colombo S, Toietta G , Zecca L , Vanoni M , Tortora P

Journal of Bacteriology (1995)

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