I studied Biopharmaceutical Sciences at Leiden University from September 2001 until September 2007. In the final years I have done two major internships. The first one was within the LACDR on a biochemical project. The second one was something completely different on a computational project at Tibotec in Mechelen Belgium. It was here that I discovered the challenging side of computational research.
I did my PhD at the group of Medicinal Chemistry Leiden in close collaboration with Tibotec in the fall of 2007 until 2012. My project focused on the development of proteochemometric modeling which can map structure activity relations between a series of compounds and a series of proteins including pair specific interaction data.Developing this technique and characterizing its advantages and possible shortcomings is the aim of my work (a collaboration between Leiden University and Jansen Belgium)
Currently I started as a postdoc in the ChEMBL group (headed by John Overington) at the European Bioinformatics Institute. The project is a cooperation between the EBI and the group of Sthephen Cusack in Grenoble.
Please see my personal website (www.gjpvanwesten.nl) for further info, publications and reprint requests.
Specialties: In silico research, modeling, machine learning, proteochemometrics, chemogenomics, QSAR, computer aided drug design
I am always interested in collaborations, so don't hesitate to contact me.
Significantly Improved HIV Inhibitor Efficacy Prediction Employing Proteochemometric Models Generated From Antivirogram Data
van Westen G
van Vlijmen H
PLoS Computational Biology(2013)
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