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Hajime Yamazaki

  • PhD
  • Research Assistant Professor
  • University of Pittsburgh School of Dental Medicine
  • 9h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 387CitationsNumber of citations received by Hajime's publications. Updated daily.


My research interests lie in discovering the mechanisms of biomineralization in vertebrate hard tissue. The current goal of my research is to elucidate how nature produces the intricate and functional tooth enamel structures with helps of extracellular matrix proteins using animal models, molecular biology methods, electron microscopes, and various surface analysis techniques. In the future, I would like to apply this knowledge of biomineralization to translational research areas such as treatment to cure diseases in the hard tissues, biomaterials to substitute the missing hard tissues, or regeneration of the hard tissues. Also, I have previously worked on dental caries, particularly in elucidating the mechanism of remineralization and demineralization of tooth enamel and dentin from physicochemical aspects.

Recent publications

  • Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor

    • Shin N
    • Yamazaki H
    • Beniash E
    • et al.
  • Trafficking and secretion of Keratin 75 by ameloblasts in vivo.

    • Yang X
    • Yamazaki H
    • Yamakoshi Y
    • et al.

Professional experience

Research Assistant Professor

School of Dental Medicine, University of Pittsburgh

December 2017 - Present

Staff Associate

Forsyth Institute

January 2013 - Present

Research Assistant

Forsyth Institute

April 2004 - December 2012(9 years)


Kao Corp

April 1995 - April 2004(9 years)

Visiting Scientist

Forsyth Institute

April 2000 - July 2002(2 years)


PhD (Dental Science)

Tohoku University Graduate School of Dentistry School of Dentistry

April 2010 - September 2012(2 years)

MS (Organometallic Chemistry)

Tohoku Daigaku

April 1993 - March 1995(2 years)

Bachelor in Chemistry

Tohoku Daigaku

April 1989 - March 1993(4 years)