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Henrik Franzyk

  • PhD
  • 26h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 1979CitationsNumber of citations received by Henrik's publications. Updated daily.

Research interests

Drug delivery via cell-penetrating peptidesSolid-phase synthesis methodsImmunodulatory peptidomimeticsAntimicrobial peptides and peptidomimetics

About

Current focus areas in research comprise design, synthesis and optimization of biologically active compounds: (i) Structure-activity studies of antibacterials and potentiators of antibiotics; (ii) Bacterial delivery of antisense antibiotics; (iii) Mechanisms and structural optimization of immunomodulating peptides and peptidomimetics; (iv) Studies towards improved macromolecular drug delivery (v) Solid-phase synthesis of unnatural amino acid and peptidomimetic building blocks.

Co-authors (213)

Publications (5)

  • Adjuvants Based on Synthetic Mycobacterial Cord Factor Analogues: Biophysical Properties of Neat Glycolipids and Nanoself-Assemblies with DDA

    • Kallerup R
    • Franzyk H
    • Schiøth M
    • et al.
    N/AReaders
    0Citations
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  • The lipidated peptidomimetic lau-((S)-Aoc)-(Lys-βNphe)<inf>6</inf>-NH<inf>2</inf> is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH oxidase

    • Holdfeldt A
    • Skovbakke S
    • Winther M
    • et al.
    N/AReaders
    7Citations
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  • The peptidomimetic Lau-(Lys-βNSpe)<inf>6</inf>-NH<inf>2</inf> antagonizes formyl peptide receptor 2 expressed in mouse neutrophils

    • Skovbakke S
    • Winther M
    • Gabl M
    • et al.
    N/AReaders
    7Citations
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  • Interaction of peptidomimetics with bilayer membranes: Biophysical characterization and cellular uptake

    • Jing X
    • Kasimova M
    • Simonsen A
    • et al.
    N/AReaders
    7Citations
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  • Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

    • Nordly P
    • Korsholm K
    • Pedersen E
    • et al.
    N/AReaders
    30Citations
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