CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Annals of neurology (2010)
GRM7 variants confer susceptibility to age-related hearing impairment
Human Molecular Genetics (2009)
Identification of genetic variants using bar-coded multiplexed sequencing
Nature Methods (2008)
SNP-based chromosomal copy number ascertainment following multiple displacement whole-genome amplification.
Chromosomal abnormality at 6p25.1-25.3 identifies a susceptibility locus for hypothalamic hamartoma associated with epilepsy.
Epilepsy Research (2007)
Commonly carried allele within FTO, an obesity-associated gene, relates to accelerated brain degeneration in the elderly
Tonic Premarin dose-dependently enhances memory, affects neurotrophin protein levels and alters gene expression in middle-aged rats.
Neurobiology of Aging (2009)
Genome-wide association study of temporal lobe structure identifies novel quantitative trait loci for neurodegeneration in alzheimer's disease
Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease-affected brain regions in cognitively normal APOEε4 carriers.
A Genome-wide Analysis Identifies Genetic Variants in the RELN Gene Associated with Otosclerosis
The American Journal of Human Genetics (2009)
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Human Molecular Genetics (2010)
Reduced Posterior Cingulate Mitochondrial Activity in Expired Young Adult Carriers of the APOE ε4 Allele, the Major Late-Onset Alzheimer's Susceptibility Gene.
Journal of Alzheimers disease JAD (2010)
SNiPer: Improved SNP genotype calling for Affymetrix 10K GeneChip microarray data
BMC Genomics (2005)
Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance.
Human Molecular Genetics (2007)
Identification of a Novel Risk Locus for Progressive Supranuclear Palsy by a Pooled Genomewide Scan of 500,288 Single-Nucleotide Polymorphisms
The American Journal of Human Genetics (2007)
Peripheral delivery of a ROCK inhibitor improves learning and working memory.
Behavioral Neuroscience (2009)
Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele.
Archives of Neurology (2010)
Common Kibra alleles are associated with human memory performance.
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Neurobiology of Aging (2010)
Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly
Proceedings of the National Academy of Sciences of the United States of America (2010)
Identification of genetic variants using bar-coded multiplexed sequencing.
Nature Methods (2008)
Voxelwise genome-wide association study (vGWAS).
The Translational Genomics Research Institute (TGen)
May 2005 - Present