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John Clayton

  • Ph.D.
  • Post-doctoral Researcher
  • IBMC-CNRS
  • 3h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 347CitationsNumber of citations received by John's publications. Updated daily.

Other IDs

Research interests

Infectious Disease; Innate Immunity; Molecular Entomology; Programmed Cell Death; Virology; Parasitology; Vaccine Design and Development

About

I was born and raised near Blythe, California. I Went to UC Berkeley and got my bachelor's degree in Molecular and Cell Biology with an emphasis in Genetics and Development. While there, I worked in the Laboratory of Brent Mishler on molecular evolution of the 3'UTR of the rbcL gene. After graduating, I worked for eighteen months in Atlanta, GA as an EID Fellow in the Laboratory of Dr. Mark Benedict on transgenesis of the malaria vector, Anopheles gambiae. In the Spring of 2003 I joined the laboratory of Dr. Fotis Kafatos at EMBL in Heidelberg, Germany, where I worked on reverse genetics, transgenesis and functional genomics of An. gambiae, specifically with respect to the insect innate immune response to Plasmodium and bacterial infections . I returned to the US in 2003 to pursue a PhD in the laboratory of Dr. J. Marie Hardwick in the W. Harry Feinstone Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health in Baltimore, MD. My thesis research involved the heterologous expression of virulence factors in Sindbis virus and the insect host response to RNA viruses, particularly in the context of a prime-challenge infection model. After earning my doctorate, I began post-doctoral work in the laboratory of Stephanie Blandin in the Anopheles Group at the Institute de Biologie Moleculaire et Cellulaire (IBMC) in Strasbourg, France. We are currently working to identify genes responsible for resistance and susceptibility to Plasmodium infection in the malaria mosquito, Anopheles gambiae. This is my second experience living abroad as an ex-pat and I am trying to make the most of it by learning French and blogging about my experiences, my research and life in general. In my spare time, I enjoy traveling, dining, film, visiting monuments, museums and parks, theater, classical and contemporary live music performances and pub crawling.

Co-authors (23)

Publications (5)

  • Silencing of Genes and Alleles by RNAi in Anopheles gambiae

    • Lamacchia M
    • Clayton J
    • Wang-Sattler R
    • et al.
    N/AReaders
    N/ACitations
  • Transduction of Virulence Factors by Alphaviruses in Vertebrate and Invertebrate Models of Infection

    • Clayton J
    N/AReaders
    N/ACitations
  • Apoptosis and Virus Infection

    • Clayton J
    • Hardwick J
    N/AReaders
    N/ACitations
  • The Evolution and Development of the Immune System

    • Clayton J
    N/AReaders
    N/ACitations
  • Germline transformation of the malaria vector, Anopheles gambiae, with the piggyBac transposable element.

    • Grossman G
    • Rafferty C
    • Clayton J
    • et al.
    N/AReaders
    N/ACitations

Professional experience

Post-doctoral Researcher

IBMC-CNRS

June 2011 - Present

Graduate Student

Johns Hopkins Bloomberg School of Public Health

August 2003 - December 2010(7 years)

Researcher

European Molecular Biology Laboratory

March 2002 - July 2003(a year)

Emerging Infectious Diseases (EID) Fellow

Centers for Disease Control and Prevention

August 2000 - February 2002(2 years)

Education

Graduate Student, PhD

Johns Hopkins Bloomberg School of Public Health

August 2003 - December 2010(7 years)

A.B Molecular and Cell Biology, Emphasis Genetics and Development

University of California at Berkeley

August 1996 - May 2000(4 years)